vLLM

The Future of AI Infra: from Kubernetes to Agent Sandboxes — Akshat Bubna, Modal CTO

Jul 8, 2026 · 59:10

Modal CTO Akshat Bubna explains how the cloud platform evolved from a serverless runtime to an AI cloud built for elastic inference, agent sandboxes, and post-training workloads. He argues that Kubernetes was never designed for bursty GPU-heavy AI workloads, so Modal built a decorator-based infrastructure that co-locates compute requirements with code. The company added GPUs a year before ChatGPT and now powers inference for custom models at Suno, Runway, and robotics firms, using GPU snapshotting to slash cold starts. Modal's new Auto Endpoints incorporate open-source DeFlash speculative decoding for frontier-level performance. For reinforcement learning rollouts, Modal provides up to 100,000 sandboxes simultaneously. The platform spans 17 cloud providers, features private IPv6 networking via eBPF, and supports serverless multi-node training with RDMA. Bubna also reveals Modal's shift from developer experience to agent experience, noting that agents benefit from the same minimalist SDK and observability tools that humans use.

⚡️ Google's Open AI Strategy — Omar Sanseviero, Google DeepMind

May 24, 2026 · 29:59

Omar Sanseviero, Google DeepMind's Head of Developer Experience, explains Gemma 4's novel architecture with per-layer embeddings that enable effective parameter offloading: only 2B of 5B parameters need GPU memory, ideal for on-device inference on phones and Raspberry Pis. The model matches 1.5-year-old state-of-the-art in most areas, with Gemini Nano integrated into Pixel and Samsung phones. Gemma 4 supports multimodal input (audio, images, short video) but not audio output or combined audio-video prompts. Sanseviero notes fine-tuning is declining as out-of-box capabilities improve, but remains relevant for specialized domains like healthcare. He contrasts dense (31B) and MoE (27B) variants, highlighting MoE's inference speed but fine-tuning challenges. The team is expanding globally, with Kaggle joining DeepMind to create community-driven benchmarks for model evaluation.

Agent Inference at the "Speed of Light" — How NVIDIA moves like a $4.3 Trillion Startup

Mar 8, 2026 · 1:26:00

NVIDIA's Nader Khalil and Kyle Kranen join Swyx and Vibhu to explain how the company moves like a $4.3 trillion startup through speed-of-light (SOL) first-principles thinking, agent security boundaries, and the Dynamo inference engine. They argue agents should only do two of three things (files, internet, code) to prevent vulnerabilities, and detail Brev's acquisition to improve developer UX with one-click GPU access and DGX Spark integration. Kyle describes Dynamo as a data center scale inference engine that optimizes serving by scaling out, using prefill/decode disaggregation, Kubernetes-based scheduling, and model-hardware co-design to improve cost, latency, and quality. The episode covers SOL's role in creating urgency, long-context limits and potential 'unhobblers' like multi-head latent attention, and the shift toward CLI-first agent workflows for enterprise tools.

⚡️Mercury: Ultra-Fast Diffusion LLMs — Estefano Ermon, CEO Inception Labs

Aug 4, 2025 · 28:07

Stefano Ermon of Inception Labs explains why diffusion language models like their Mercury Coder can match GPT-4.1 Nano and Claude Haiku in intelligence while delivering 5–10× faster inference at 737–1109 tokens/sec on H100s, built on score-based generative model foundations he pioneered at Stanford. He details the coarse-to-fine generation process that modifies multiple tokens per network evaluation, the required end-to-end training from scratch (no fine-tuning existing LLMs), and how post-training pipelines use specialized DPO for preference alignment. Ermon identifies latency-sensitive applications—voice agents, IDEs, vibe coding—as the killer use case, acknowledges they aren't yet frontier-level but sees a future where diffusion dominates due to efficiency gains, and notes the challenge of open-sourcing given proprietary inference engines and kernels.

The Shape of Compute (Chris Lattner of Modular)

Jun 13, 2025 · 1:18:18

Chris Lattner of Modular explains how his company is breaking the CUDA monopoly with Mojo and MAX, matching NVIDIA's best inference performance on AMD and NVIDIA GPUs. After three years in R&D, Modular open-sourced its stack and now delivers state-of-the-art Llama 3 serving at over 800 tokens per second. Mojo, a Python-family language, runs kernels faster than Rust and can extend Python without bindings, while MAX provides a full inference framework with automatic kernel fusion and cluster management. Unlike VLLM or SGLang, Modular's container is just a gigabyte, fully open source, and not reliant on proprietary CUDA blobs. DeepSeek's low-level PTX work validated the approach, but Lattner emphasizes that Mojo's portability avoids rewriting kernels for each new GPU architecture. He also details his daily routine, using Cursor for coding, and hiring "elite nerds" to grow the team.

Outlasting Noam Shazeer, Crowdsourcing Chai AI w/ 1.4m DAU — with William Beauchamp, Chai Research

Jan 26, 2025 · 1:13:33

William Beauchamp, founder-CEO of Chai AI, explains how he pivoted from algorithmic trading to build a character chatbot platform before Character.ai, growing to 1.4M DAU and $22M+ revenue by crowdsourcing model improvements through Chaiverse. Starting with GPT-J in 2021, he found product-market fit with a therapist bot and shifted to user-generated content, letting users define prompts, images, and names. Competing against well-funded rivals like Character AI and Talkie, Chai ships over 100 LLMs weekly via its developer platform, spending $10M on compute in 2024 and tripling it. Beauchamp argues AI follows an S-curve, not scaling laws, and focuses on inference optimization using rejection sampling and reward models to serve better responses. He prioritizes 'insanely great' products over technology-driven features, noting that audio and image features failed to move metrics, while a data flywheel and aggressive user acquisition drove rapid growth.

DeepSeek V3, SGLang, and the state of Open Model Inference in 2025 (Quantization, MoEs, Pricing)

Jan 19, 2025 · 57:18

Amir Haghighat and Yineng Zhang from Baseten explain how they serve DeepSeek V3, a 671-billion-parameter MoE model requiring H200 clusters with FP8 support, making it the top open-weights model. They detail Baseten’s dedicated inference model (no shared endpoints) and its reliance on SGLang for performance gains like Radix prefix caching and MLA attention support. Yineng highlights SGLang’s edge over vLLM and TensorRT-LLM in usability and customization, especially for large models. Amir outlines three pillars for mission-critical inference: model-level performance (via frameworks like SGLang), horizontal scaling across regions and clouds, and low-latency multi-model workflows. The episode also covers quantization trends, MoE architecture, and speculative decoding as key enablers for open model deployment.

Building the Silicon Brain - Drew Houston of Dropbox

Oct 18, 2024 · 1:11:40

Drew Houston, CEO of Dropbox, details his hands-on AI engineering journey and the company's strategic pivot to AI-first products like Dropbox Dash for universal search and access control. Having spent over 400 hours coding with LLMs, he built personal tools that seeded Dropbox AI, including a file question-answering system. He advocates 'rent, don't buy' for AI infrastructure, relying on open-source models and keeping options open as costs drop 10-100x yearly. Houston explains Dropbox's advantage in trust and data privacy, positioning it as a neutral platform that integrates with Google Drive and OneDrive. He discusses staying relevant through constant learning and founder mode, and advises founders to systematically train skills ahead of their company's growth.

[Paper Club] Writing in the Margins: Chunked Prefill KV Caching for Long Context Retrieval

Sep 19, 2024 · 53:53

Umar Jamil from Writer presents 'Writing in the Margins,' a paper on improving long-context retrieval in LLMs by leveraging chunked prefill of the KV cache. The method splits a long prompt into chunks, generates query-relevant annotations (margins) after each chunk, and appends them at the end before generating the final answer. This approach solves the 'lost in the middle' problem without fine-tuning, and unlike traditional RAG or separate summarization, it avoids re-prefilling the entire context, reducing cost from double to single prefilling. The technique is compatible with any transformer model and includes overlapping margin generation and classification within the same batch request. Benchmarks show consistent improvements across models, and the implementation is open-source on GitHub.

Answer.ai & AI Magic with Jeremy Howard

Aug 17, 2024 · 1:11:00

Jeremy Howard of Answer.AI argues that continuous pre-training should be treated as a continuum, not separate phases, and demonstrates how FSDP+QLoRA enables training a 70B model on just two NVIDIA 4090s. He reveals Answer’s non-hierarchical, manager-free R&D lab model that recruited unusual talent like Benjamin Warner and Ben Claviez, who independently launched BERT 24 to revive encoder-only architectures. Howard introduces FastHTML, a pure-Python web framework built on HTMX and Starlette, for creating modern SPAs without JavaScript. He previews “AI Magic,” a dialogue engineering system that moves beyond teletype-style chat interfaces and code editors, aiming to make AI-assisted development more interactive. The episode also covers Answer’s Public Benefit Corporation structure designed to resist hostile takeovers, and critiques decoder-only hype while advocating for encoder-decoder and state-space models.

[LLM Paper Club] Llama 3.1 Paper: The Llama Family of Models

Jul 29, 2024 · 1:23:46

This episode examines Meta's Llama 3.1 paper, detailing the 405B dense model, its scaling laws grounded on the ARC reasoning benchmark rather than perplexity, and the decision to train on 15 trillion tokens. Vibhu explains the training infrastructure: 16,000 H100s over 54 days with 419 interruptions, 78% from GPU hardware failures. Eugene Yan walks through the synthetic data pipeline—using Llama 2 for filtering, stepwise reward models, and Monte Carlo tree search to improve reasoning traces. Hassan shares building LlamaTutor.com with Together API, serving 4,000 visitors and 5,900 requests for about $12. The group also discusses quantization trade-offs (larger models degrade less), inference provider variability (Groq's non-deterministic temperature zero), and compares Llama 405B's performance to GPT-4o and Claude.