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⚡️ Prism: OpenAI's LaTeX "Cursor for Scientists" — Kevin Weil & Victor Powell, OpenAI for Science
Jan 27, 2026 · 36:00
Kevin Weil (VP of OpenAI for Science) and Victor Powell (Prism product lead) launch Prism, a free AI-native LaTeX editor that embeds GPT-5.2 directly into the scientific writing workflow, eliminating copy-pasting between ChatGPT and Overleaf and turning weeks of LaTeX formatting into minutes of natural language instruction. The origin story reveals Kevin discovered Victor's stealth company Cricket on Reddit and DM'd him to bring the team into OpenAI. In the live demo, Prism proofreads papers paragraph by paragraph, converts a whiteboard commutative diagram photo into TikZ code, generates 30 pages of general relativity lecture notes in seconds, and verifies complex symmetry equations in parallel chat sessions. They argue that LaTeX typesetting is the bottleneck diverting scientists from actual research, and that unlimited free collaboration and multi-line diff generation make Prism a 'tool for thought' rather than just a publishing tool. Kevin predicts 2026 will be for AI in science what 2025 was for AI in software engineering — a year when it becomes essential. The discussion also covers OpenAI's approach to accelerating science broadly, including the role of robotic labs and…

The Rise and Fall of the Vector DB category: Jo Kristian Bergum (ex-Chief Scientist, Vespa)
Apr 19, 2025 · 27:17
Jo Kristian Bergum argues that the vector database category is dying because vector search capabilities have converged into existing databases like Postgres' pgvector, Elasticsearch, and Vespa, making specialized vector databases unnecessary for most use cases. He traces the category's rapid rise after ChatGPT, driven by the misconception that RAG required embeddings, and notes Pinecone's high ARR and subsequent repositioning. Bergum emphasizes that embeddings remain important but should be combined with traditional retrieval methods like BM25 for effective search, and that re-ranking can add modest gains. He critiques the hype around knowledge graphs, noting the bottleneck of building them, but sees LLMs making triplet generation easier. For the future, he hopes for more domain-specific embedding models and visual language model backbones, though acknowledges the difficulty of the business model.
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