How Zyphra went all-in on AMD + Why Devs feel faster with AI but are slower — with Quentin Anthony
Nov 3, 2025 · 1:00:02
Quentin Anthony, head of model training at Zyphra and advisor at EleutherAI, explains why his company moved all training to AMD MI300X GPUs, outperforming Nvidia H100s on certain workloads thanks to 192GB VRAM and higher memory bandwidth, and describes his kernel development approach of writing directly in ROCm or GPU assembly rather than using Triton. He also shares his experience in the METR study on AI coding productivity, where he was one of the few developers with measurable speedup, and offers tips: timebox AI use, avoid the slot machine effect, maintain context hygiene, and use direct API over tools like Cursor. Additionally, he argues that open source AI research benefits from siloed focused teams with guaranteed funding over grand collaborations, and notes that kernel datasets alone won't solve GPU programming due to evaluation challenges.
